In this procedure, a small amount of heart muscle tissue is removed and tested for signs of inflammation or infection. Tricuspid valve regurgitation sometimes occurs during the placement or removal of pacemaker and defibrillator wires, which cross the tricuspid valve. Experiencing trauma to the chest, such as in a car accident, may cause damage that leads to tricuspid valve regurgitation. In this rare condition, tumors that develop in the digestive system and spread to the liver or lymph nodes produce a hormonelike substance that can damage heart valves, most commonly the tricuspid valve and pulmonary valves. An infection of the lining of the heart can damage the tricuspid valve. Infection of the lining of the heart (infective endocarditis).This complication of untreated strep throat can damage the tricuspid valve and other heart valves, causing valve regurgitation later in life. Marfan syndrome is a connective tissue disorder occasionally associated with tricuspid valve regurgitation. In this condition, the tricuspid valve is malformed and sits lower than usual in the right ventricle. Tricuspid valve regurgitation in children is usually caused by a rare congenital heart defect called Ebstein anomaly. Some congenital heart defects can affect the shape and function of the tricuspid valve. Heart defects present at birth (congenital heart defects).Tricuspid valve regurgitation can be caused by: As a result, blood leaks backward into the right atrium. In tricuspid valve regurgitation, the tricuspid valve doesn't close tightly. The valve flaps then close tightly to prevent the blood from moving backward. These valve flaps open to let blood flow from the upper right chamber (right atrium) to the lower right chamber (right ventricle). The tricuspid valve consists of three thin flaps of tissue (called cusps, or leaflets). The tricuspid valve sits between the heart's two right chambers. The condition may occur with a hole between the two upper chambers of the heart, called an atrial septal defect. The tricuspid valve is incorrectly formed and located lower than usual in the heart. This means it's a congenital heart defect. Ebstein anomaly is a rare heart problem present at birth.
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